Affimed Announces Clinical Updates at the Annual Meeting of the American Association for Cancer Research
In a Clinical Trials Plenary Session an update of the phase 1/2 study evaluating cord blood-derived NK cells that are pre-complexed with the innate cell engager AFM13 in patients with CD30-positive lymphomas will be presented
A poster on the dose-escalation phase of the clinical trial with AFM24 monotherapy in patients with solid tumors will be presented
HEIDELBERG, Germany, March 08, 2022 (GLOBE NEWSWIRE) -- Affimed N.V. (Nasdaq: AFMD), a clinical-stage immuno-oncology company committed to giving patients back their innate ability to fight cancer, today announced that two abstracts with clinical data of its innate cell engagers (ICE®) have been accepted for presentation at the annual meeting of the American Association for Cancer Research (AACR), taking place April 8-13, 2022 in New Orleans, Louisiana.
The two events include an oral presentation with an update of the study that evaluates AFM13 pre-complexed with NK cells in patients with CD30-positive lymphomas and a poster presentation with data of the dose-escalation phase of the AFM24 monotherapy study for solid tumor treatment.
Oral presentation details:
Title: Innate cell engager (ICE®) AFM13 combined with preactivated and expanded cord blood (CB)-derived NK cells for patients with refractory/relapsed CD30+ lymphoma
Presentation: CT003
Authors: Yago Nieto, Pinaki Banerjee, Indreshpal Kaur, Roland Bassett, Lucila Kerbauy, Rafet Basar, Mecit Kaplan, Lori Griffin, Daniel Esqueda, Christina Ganesh, Melissa Barnett, Amin Alousi, Chitra Hosing, Jeremy Ramdial, Neeraj Saini, Samer Srour, Karenza Alexis, Andreas Harstrick, Elizabeth J Shpall, Katayoun Rezvani
Session: Clinical Trials of Cellular Immunotherapies, Sunday, April 10, 1:00 - 3:00 p.m. CDT
Poster details:
Title: A phase 1/2a first-in-human study of AFM24, a CD16A/epidermal growth factor (EGFR) bispecific Innate Cell Engager (ICE®), in patients with locally advanced or metastatic EGFR-expressing solid tumors: Preliminary findings from the dose-escalation phase
Abstract number: CT149
Authors: Anthony El-Khoueiry, Juanita Lopez, Omar Saavedra, Mark Awad, Jacob Thomas, Crescens Tiu, Elena Garralda, Bettina Rehbein, Gabriele Hintzen, Kerstin Pietzko, Christa Raab, Erich Rajkovic, Paulien Ravenstijn, Michael Emig
Session: Phase I Clinical Trials 1, Monday, April 11, 1:30 p.m. - 5:00 p.m. CDT
Abstract release: The full abstract will become public at 1:00 p.m. ET on Friday, April 8